{"id":30358,"date":"2025-10-09T14:07:11","date_gmt":"2025-10-09T14:07:11","guid":{"rendered":"https:\/\/www.dementiauk.org\/?page_id=30358"},"modified":"2025-11-07T15:45:57","modified_gmt":"2025-11-07T15:45:57","slug":"statins","status":"publish","type":"page","link":"https:\/\/www.dementiauk.org\/information-and-support\/health-advice\/statins\/","title":{"rendered":"Understanding statins and dementia"},"content":{"rendered":"<p><!--StartFragment --><\/p>\n<p><span class=\"cf0\">Statins are a type of <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/health-advice\/medication-for-dementia\/\">medication<\/a> prescribed to reduce cholesterol and prevent heart disease and related complications, such as heart attacks and strokes. <\/span><\/p>\n<p><span class=\"cf0\">While some people are concerned that statins could cause dementia, research shows that for people with high cholesterol or heart disease, taking a prescribed statin may prevent damage to the brain and blood vessels and reduce the risk of dementia. <\/span><\/p>\n<p><span class=\"cf0\">Our <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/how-we-can-support-you\/what-is-an-admiral-nurse\/\">dementia specialist Admiral Nurses<\/a> explain what statins are, what they are used for and how they might help to <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/about-dementia\/can-dementia-be-prevented-how-to-lower-your-risk\/\">reduce the risk<\/a> of dementia. <\/span><\/p>\n<h2><span class=\"cf0\">What is cholesterol?<a id=\"cholesterol\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">Cholesterol is a fatty substance that is made by the body and is also in some of the foods we eat. We all need cholesterol to keep our cells healthy, but too much of the wrong type can cause health problems. <\/span><\/p>\n<p><span class=\"cf0\">There are two types of cholesterol: <\/span><\/p>\n<ul>\n<li><span class=\"cf0\">low-density lipoprotein (LDL) or non-high-density lipoprotein (non-HDL): this is often known as \u2018bad cholesterol\u2019 as it leads to a build-up of fat in the arteries, which can be dangerous <\/span><\/li>\n<li><span class=\"cf0\">high-density lipoprotein (HDL): this is often known as \u2018good\u2019 cholesterol as it removes \u2018bad\u2019 cholesterol from the body <\/span><\/li>\n<\/ul>\n<p><span class=\"cf0\">On this page, when we use the term \u2018high cholesterol\u2019, we are referring to \u2018bad\u2019 LDL cholesterol. <\/span><\/p>\n<h2><span class=\"cf0\">What are statins?<a id=\"statins\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">Statins are a group of medications used to help lower cholesterol levels. They come as tablets to be taken once a day. <\/span><\/p>\n<h3><span class=\"cf0\">How do statins affect the body and brain? <\/span><\/h3>\n<p><span class=\"cf0\">High levels of cholesterol can cause fat to build up in the arteries. This narrows the arteries, which can interrupt the blood supply to the body and brain and lead to health problems like heart disease and strokes. These fatty deposits can also break off and cause clots in the blood vessels. This can happen anywhere in the body, including the brain. <\/span><\/p>\n<p><span class=\"cf0\">Statins work by blocking a specific enzyme which the liver uses to produce cholesterol, reducing the levels in the body. They can\u2019t remove any existing fatty build-up in the arteries, but they can stop it getting worse. <\/span><\/p>\n<h2><span class=\"cf0\">Why are statins prescribed?<a id=\"prescribed\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">Statins are prescribed to reduce cholesterol levels and help to prevent further damage to the arteries. <\/span><\/p>\n<h2><span class=\"cf0\">What conditions are statins prescribed for?<a id=\"conditions\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">Statins may be prescribed for people who have high cholesterol or cardiovascular disease (CVD). They may also be prescribed for people who are at risk of developing CVD within the next 10 years. This risk is based on the person\u2019s personal and family history. <\/span><\/p>\n<p><span class=\"cf0\">CVD includes: <\/span><\/p>\n<ul>\n<li><span class=\"cf0\">coronary heart disease: a restriction in blood supply to the heart <\/span><\/li>\n<li><span class=\"cf0\">angina: chest pain caused by reduced blood flow to the heart <\/span><\/li>\n<li><span class=\"cf0\">heart attacks: when the supply of blood to the heart is suddenly blocked <\/span><\/li>\n<li><span class=\"cf0\">stroke: this happens when the supply of blood to the brain becomes blocked <\/span><\/li>\n<li><span class=\"cf0\">transient ischaemic episodes (TIAs): \u2018mini strokes\u2019 <\/span><\/li>\n<\/ul>\n<h3><span class=\"cf0\">Cholesterol and dementia <\/span><\/h3>\n<p><span class=\"cf0\">Research has shown that people who have high cholesterol between the ages of 40 and 60 are at an increased risk of developing dementia. <\/span><\/p>\n<p><span class=\"cf0\">High cholesterol can lead to a build-up of proteins in the brain which form \u2018plaques\u2019 and \u2018tangles\u2019 that are linked to <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/types-of-dementia\/alzheimers-disease\/\">Alzheimer\u2019s disease<\/a>. <\/span><\/p>\n<p><span class=\"cf0\">The blockages in arteries caused by high cholesterol levels can also lead to conditions like high blood pressure and stroke, which can increase the risk of <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/types-of-dementia\/vascular-dementia\/\">vascular dementia<\/a>. <\/span><\/p>\n<h2><span class=\"cf0\">Do statins increase the risk of developing dementia?<a id=\"risk\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">People sometimes worry that taking statins could increase the risk of developing dementia. This could be because a small number of people develop some memory loss and confusion when they start taking statins, which they may attribute to dementia. <\/span><\/p>\n<p><span class=\"cf0\">However, these symptoms are side effects of the medication and are reversed if the person stops taking statins, unlike the <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/about-dementia\/signs-and-symptoms-of-dementia\/\">symptoms of dementia<\/a>, which cannot be reversed and always get worse over time. <\/span><\/p>\n<h2><span class=\"cf0\">Evidence of statins lowering dementia risk<a id=\"evidence\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">Studies have shown that people who are taking appropriately prescribed statins are around 20% less likely to develop all <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/types-of-dementia\/\">forms of dementia<\/a> than those who aren\u2019t taking statins. <\/span><\/p>\n<p><span class=\"cf0\">However, taking statins where there is no reason to do so has no benefit on memory or thinking skills. <\/span><\/p>\n<h3><span class=\"cf0\">Statins and Alzheimer\u2019s disease risk <\/span><\/h3>\n<p><span class=\"cf0\">Studies have shown statins reduce the risk of Alzheimer\u2019s disease by around 30% in people with high cholesterol, CVD or a high risk of CVD, compared to those who aren\u2019t taking statins. <\/span><\/p>\n<h3><span class=\"cf0\">Statins and vascular dementia risk <\/span><\/h3>\n<p><span class=\"cf0\">People who are taking appropriately prescribed statins are around 7% less likely to develop vascular dementia. <\/span><\/p>\n<h3><span class=\"cf0\">Ongoing research <\/span><\/h3>\n<p><span class=\"cf0\">Research into the impact of statins on dementia is ongoing. There is evidence that if someone is taking statins for high cholesterol, taking them as prescribed on a long-term basis could help. However, taking statins is not thought to reduce the risk of dementia in people who have healthy cholesterol levels. <\/span><\/p>\n<p><span class=\"cf0\">More research is needed into how statins could affect the chances of developing dementia. <\/span><\/p>\n<h2><span class=\"cf0\">Questions to ask your healthcare provider before starting statins<a id=\"questions\"><\/a> <\/span><\/h2>\n<p><span class=\"cf0\">There are a range of questions you can ask before starting to take statins, including: <\/span><\/p>\n<ul>\n<li><span class=\"cf0\">What are the potential side effects? <\/span><\/li>\n<li><span class=\"cf0\">What should I do if I experience side effects? <\/span><\/li>\n<li><span class=\"cf0\">Could these interact with any existing medications I am taking? <\/span><\/li>\n<li><span class=\"cf0\">What other changes should I make while taking them?<\/span><\/li>\n<li>Are there any alternatives to taking statins?<\/li>\n<li>Lifestyle changes like eating a healthy diet, getting regular exercise, stopping smoking and keeping alcohol consumption within recommended limits can also reduce cholesterol levels<\/li>\n<\/ul>\n<h2><span class=\"cf0\">How we can support you<a id=\"support\"><\/a><\/span><\/h2>\n<p>To speak to a dementia specialist Admiral Nurse about statins or any other aspect of dementia, please call our free <a href=\"https:\/\/www.dementiauk.org\/information-and-support\/specialist-diagnosis-and-support\/admiral-nurse-dementia-helpline\/\">Dementia Helpline<\/a>\u00a0on 0800 888 6678 (Monday-Friday 9am-9pm, Saturday and Sunday 9am-5pm, every day except 25th December) or email\u00a0<a href=\"mailto:helpline@dementiauk.org\">helpline@dementiauk.org<\/a>. Alternatively, you can\u00a0<a href=\"https:\/\/www.dementiauk.org\/information-and-support\/specialist-diagnosis-and-support\/book-a-virtual-appointment\/\">pre-book a phone or video call<\/a>\u00a0with an Admiral Nurse.<\/p>\n<p><!--EndFragment --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Statins are a type of medication prescribed to reduce cholesterol and prevent heart disease and related complications, such as heart attacks and strokes. While some people are concerned that statins could cause dementia, research shows that for people with high cholesterol or heart disease, taking a prescribed statin may prevent damage to the brain and [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":2400,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"on","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"class_list":["post-30358","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Understanding statins and dementia - Dementia UK<\/title>\n<meta name=\"description\" content=\"Understand what statins are, their impact on dementia and who may benefit from taking them.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.dementiauk.org\/information-and-support\/health-advice\/statins\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Understanding statins and dementia\" \/>\n<meta property=\"og:description\" content=\"Dementia UK is a charity that provides Admiral Nurses for families affected by dementia. 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